Vitamin B12 (Cobalamin)

Test/Investigation

Vitamin B12 (Cobalamin)

Site(s) or Laboratory offering Test/Investigation

NNUH, QEH, JPUH

Units

ng/L

Comments/Precautions

Total B12 levels < 300 ng/L are reflex tested for holotranscobalamin (HoloTC). HoloTC has greater diagnostic accuracy for B12 deficiency. Levels should always be interpreted in conjunction with haematological and clinical findings. Neurological features of Vitamin B12 deficiency can occur without anaemia.

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

1 hour / 4 hour / by 8am next day

Reference intervals (adult unless stated)

187 – 883 ng/L

If UKAS Accredited Test indicate at which site

Y NNUH, QEH

Source

Abbott Alinity kit insert [G71350R01]