Test/Investigation
Anti-Phospholipid Antibodies
Site(s) or Laboratory offering Test/Investigation
NNUH
Units
U/mL
Also Known as/Frequency of Test
IgG Cardiolipin antibody; β-2-glycoprotein I antibody; Cardiolipin, Phospholipids, APS Ab
Indications
Anti phospholipid syndrome (APS) presents with thrombosis (arterial and venous) and recurrent miscarriage. It is more common in the context of other CTD such as SLE and antibody levels do not correlate with extent or severity of thrombosis. Antibodies may occur transiently following infection. To confirm the diagnosis antibodies must be identified on 2 occasions >12 weeks apart.
Sample type
Serum
Turnaround times (TAT) Urgent/Routine/GP or OPD
1 week
Reference intervals (adult unless stated)
0.0 – 10.0 U/mL Negative
10.0 –40 0.0 U/mL Equivocal
>40 U/ml Positive
If UKAS Accredited Test indicate at which site
Y NNUH