Test/Investigation
Smooth Muscle Antibodies
Site(s) or Laboratory offering Test/Investigation
NNUH (Immunology)
Units
Titre
Also Known as/Frequency of Test
SMA, SMA Titre, F-Actin, Liver autoantibodies, Autoimmune screen
Indications
Smooth muscle auto-antibodies are associated with autoimmune chronic active hepatitis (CAH). Sensitivity of 70% and up to 50% of patients with primary biliary cirrhosis. These antibodies often occur as a 'false positive' in patients with viral infections. Low titre results in patients with normal liver function are of limited clinical significance
Comments/Precautions
This test may be reflexed from findings on autoantibody screen
Sample type
Serum
Turnaround times (TAT) Urgent/Routine/GP or OPD
2 working days
Reference intervals (adult unless stated)
Negative
If UKAS Accredited Test indicate at which site
Y NNUH