Centromere antibodies

Test/Investigation

Centromere antibodies

Site(s) or Laboratory offering Test/Investigation

NNUH

Units

U/ml

Also Known as/Frequency of Test

CENP; CENPB; ANA

Indications

Seen in 55-70% of patients with Limited Systemic Scleroderma, and in 15% of those with the diffuse form. The specificity of this test is >98%.

Comments/Precautions

Performed as part of ANA (see above)

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 working days

Reference intervals (adult unless stated)

0.0 – 7.0 U/ml Negative
7.0– 10.0 U/mL Equivocal
>10 U/mL Positive

If UKAS Accredited Test indicate at which site

Y NNUH