Complement levels

Test/Investigation

Complement levels

Site(s) or Laboratory offering Test/Investigation

NNUH

Units

g/L

Also Known as/Frequency of Test

C3/C4

Indications

Low C3 / C4 is useful in the investigation of glomerulonephritis, SLE, cryoglobulinaemia and Hereditary angioedema. Many other conditions can activate the complement pathways and result in low complement levels.

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 working days

Reference intervals (adult unless stated)

C3 = 0.75 – 1.65 g/L
C4 = 0.14 – 0.54 g/L

If UKAS Accredited Test indicate at which site

Y NNUH