Ganglioside antibodies

Test/Investigation

Ganglioside antibodies

Site(s) or Laboratory offering Test/Investigation

Referral laboratory

Units

%

Also Known as/Frequency of Test

Anti- Ganglioside antibodies, GANG, GM1, GQ1b

Indications

Associated with several immunologically mediated peripheral neuropathies e.g. anti-GM1 (IgM) with multifocal motor neuropathy, GQ1b (IgG) with the Miller-Fisher syndrome and GM1 (IgG) with the Guillain-Barre syndrome. NB they can be found at low titres in healthy individuals.

Comments/Precautions

Referred outside of EPA

Sample type

Serum

Turnaround times (TAT) Urgent/Routine/GP or OPD

2 weeks

Reference intervals (adult unless stated)

<30% Negative
30 – 50% Grey Zone
51 – 100% Positive
>100% Strongly Positive